Larger waist? You have an increased colon cancer risk.
Each 1 cm rise in waist size = increased risk.
1 cm = slightly > 1/3rd of inch!
Spink Health 2015
Probably due to increased inflammation due to fat cells inside abdominal cavity and between organs, not the fat underneath the skin.
So wanting to be healthfully svelte is not just being a slave to vanity, but to colon safety.