Many California and other state wines found to contain arsenic. Arsenic is an endocrine disruptor of the insulin receptor, contributing to insulin resistance.
In this study on 65 US wines, Washington wines had the highest level of arsenic and Oregon had the lowest.
This is an issue only if you drink wine regularly, but these days, that covers a lot of folks.
I was a reader on a WHO paper on the new causes of the diabetes epidemic and we had a whole section on heavy metals, especially arsenic. It tends not to bioaccumulate in tissues, but daily exposure is a health threat. And, it can come from wine.
Should you give up your wine?
Probably not.
But you should include regular detox strategies in your health plans.

Denise Wilson. Arsenic Content in American Wine. Journal of Environmental Health, October 2015, Volume 78, No. 3